Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific, actinin binding activity, and ankyrin repeat binding activity. Involved in several processes, including negative regulation of protein sumoylation, postsynapse to nucleus signaling pathway, and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus, cellular response to lipopolysaccharide, and positive regulation of interleukin-12 production. Located in several cellular components, including chromatin, cytosol, and glutamatergic synapse. Is expressed in several structures, including alimentary system, early conceptus, genitourinary system, musculature, and skin. Human ortholog(s) of this gene implicated in ductal carcinoma in situ, lung non-small cell carcinoma, lymphoma, and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit).
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | ELISA, WB |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Polyclonal Antibody |
| Organism Species | Mouse |
| Concentration | – |
| Product Synonyms | [KO Validated] RELA |
| Observed Mol Wt | 60kDa |
| Alternative Names | lA, p65, p65 NF-kappa B, p65 NFkB |
| Immunogen (Antigen) | Recombinant protein |
| Format | Liquid |
| Buffer Formulation | 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
| Reactivity | Human |
| Uniprot ID | 19697 |
| Gene ID | Q04207 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cell Biology, Developmental Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
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