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Cancer

SHP2 Rabbit Polyclonal Antibody [KO Validated]

Name: SHP2 Rabbit Polyclonal Antibody [KO Validated]
SKU: KDXB200608
Availability: InStock

$100.00 – $430.00

SKU:KDXB200608 Categories:Polyclonal Antibodies

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, IP, WB
Host Species	Rabbit
Ig Isotype	IgG
Antibody Type	Polyclonal Antibody
Organism Species	Human
Concentration	–
Product Synonyms	[KO Validated] SHP2
Observed Mol Wt	68kDa
Alternative Names	BPTP3, CFC, JMML, METCDS, NS1, P2, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	50% glycerol, PBS with 0.09% Sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	5781
Gene ID	Q06124
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation, Neuroscience
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.