The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains – a RING, a B-box type 1 and a B-box type 2 – and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Pack Size | 100ul, 1ml, 20ul |
---|---|
Applications | ELISA, WB |
Host Species | Rabbit |
Ig Isotype | IgG |
Antibody Type | Polyclonal Antibody |
Organism Species | Human |
Product Synonyms | TRIM24 |
Observed Mol Wt | 117kDa |
Alternative Names | PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; TRIM24 |
Immunogen (Antigen) | Recombinant protein |
Format | Liquid |
Buffer Formulation | 50% glycerol, PBS with 0.01% thimerosal, pH7.3 |
Reactivity | Human |
Uniprot ID | 8805 |
Gene ID | O15164 |
Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
Usage | For Research Use Only. Not for diagnostics or human use. |
Shelf Life | 12 months at time of shipping |
Shipping | Shipped in Dry Ice at -20 Degree Celsius |
Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
Research Areas | Cancer, Cell Biology, Hormone Metabolism, Immunology |
KD/KO Validated | KD Validated |
Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |
Related Products
-
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View Add to wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist -
Sale
Select options This product has multiple variants. The options may be chosen on the product page Quick View View wishlist
Reviews
There are no reviews yet.