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Cancer

VHL Mouse Monoclonal Antibody

Name: VHL Mouse Monoclonal Antibody
SKU: KDXB214587
Availability: InStock

$110.00 – $430.00

SKU:KDXB214587 Categories:Monoclonal Antibodies

This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma.

Pack Size	100ul, 1ml, 20ul
Applications	ELISA, IF/ICC, IHC-P, IP, WB
Host Species	Rabbit
Ig Isotype	IgG1, kappa
Antibody Type	Monoclonal Antibody
Organism Species	Human
Product Synonyms	VHL
Observed Mol Wt	24kDa
Alternative Names	RCA1; VHL1; pVHL; HRCA1; VHL
Immunogen (Antigen)	Recombinant protein
Format	Liquid
Buffer Formulation	PBS with 0.02% sodium azide, pH7.3
Reactivity	Human, Mouse, Rat
Uniprot ID	7428
Gene ID	P40337
Potency (Clone Number)	AMC0490
Purification	Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Usage	For Research Use Only. Not for diagnostics or human use.
Shelf Life	12 months at time of shipping
Shipping	Shipped in Dry Ice at -20 Degree Celsius
Storage	Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody.
Research Areas	Cancer, Cell Biology, Immunology, Inflammation
KD/KO Validated	KD Validated
Disclaimer	The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use.