25-OH-VD, is the primary circulating form of vitamin D in human body after its initial metabolism. It serves as the preferred biomarker for assessing vitamin D status due to its plasma concentration accurately reflecting total body stores. Derived from the hydroxylation of vitamin D precursors (vitamin D3 or D2) in the liver, 25-OH-VD is a precursor to the biologically active 1,25-(OH)2-D3 formed in the kidneys. Its long half-life and stable levels make it the standard analyte for laboratory tests to diagnose vitamin D deficiency or excess, crucial in preventing and treating conditions like osteoporosis, rickets, and various chronic diseases linked to vitamin D, including cardiovascular issues, immune disorders, muscle dysfunction, diabetes, and certain cancers.
| Pack Size | 100ul, 1ml, 20ul |
|---|---|
| Applications | DB, ELISA |
| Host Species | Rabbit |
| Ig Isotype | IgG |
| Antibody Type | Monoclonal Antibody |
| Product Synonyms | Vitamin D (25-OH-VD) |
| Immunogen (Antigen) | Chemical compounds |
| Format | Liquid |
| Buffer Formulation | 0.05% BSA, 50% glycerol, PBS with 0.05% proclin300, pH7.3 |
| Reactivity | Species independent |
| Potency (Clone Number) | ARC66208 |
| Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography |
| Usage | For Research Use Only. Not for diagnostics or human use. |
| Shelf Life | 12 months at time of shipping |
| Shipping | Shipped in Dry Ice at -20 Degree Celsius |
| Storage | Store at -20 Degree Celsius. It is recommended to aliquot and store to avoid repeated freeze-thaw as it affects the stability of the antibody. |
| Research Areas | Cell Biology, Developmental Biology, Immunology |
| KD/KO Validated | KD Validated |
| Disclaimer | The data indicated herein are as indicated and validated in our laboratory. These reagents are for research use only and not for in-vitro diagnostics or human use. |

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